
By
Dr Ran Crooke


Blood Flow Restriction (BFR) training, also known as Kaatsu training, is a revolutionary approach to resistance training that utilises restricted blood flow to induce a range of positive physiological effects. Originated in the 1960s by Dr Yoshiaki Sato in Japan, BFR training offers significant strength and muscle size gains with lighter training loads, making it particularly advantageous for injury rehabilitation. This form of exercise serves as a valuable addition to regular training routines, especially for individuals on the go or facing limited access to a gym facility.
Muscle Physiology and the Effects of BFR
Muscle fibres consist of microfilaments within the muscle cells that interact to enable muscle contraction and strength development. The sliding filament model describes the interaction between actin and myosin microfilaments, which is vital for muscle contraction during strength training. Exercise triggers anabolic signalling pathways that promote muscle growth by stimulating muscle fibres. The extent of fibre activation depends on the type and intensity of the exercise. High-load exercises activate a larger portion of the musculature, while low-load exercises initially activate fewer muscle fibres. However, repeated low-load exercises can eventually lead to comparable fibre activation over time.
BFR training has a distinct impact on muscle physiology. By restricting blood flow to the muscles during low-intensity exercise, it creates an environment where metabolic by-products, such as lactate, accumulate within the muscle. This accumulation of lactate induces greater muscle workload, resulting in the formation of more cross-bridges and enhanced muscle activation and growth. Although high-load and low-load exercises under BFR may initially activate muscle fibres differently, both methods can ultimately lead to comparable muscle fibre activation. The additional muscle activation forced by BFR through metabolite accumulation explains the effectiveness of BFR training.
Benefits of Blood Flow Restriction Training
BFR training stands out due to its ability to promote muscle growth and strength gains even with lighter loads, making it a versatile exercise strategy suitable for a broad demographic.
Increased Muscle Hypertrophy: BFR training creates an environment rich in growth hormones and metabolites like lactic acid, encouraging muscle growth. It also activates fast-twitch muscle fibres, leading to increased muscle protein synthesis and size.
Enhanced Muscular Strength: Despite involving lighter weights, BFR training can significantly improve muscular strength by creating metabolic stress and activating more muscle fibres.
Improved Cardiovascular Endurance: BFR training has the potential to enhance aerobic performance by improving the body's buffering capacity, stimulating the growth of new capillaries in muscles, optimising oxygen and nutrient delivery, and facilitating waste product removal.
Faster Recovery and Rehabilitation: BFR training accelerates injury recovery and rehabilitation by promoting muscle growth and strength gains without heavy loads. It helps preserve muscle mass during injury or post-surgery recovery and enhances metabolic activity to expedite the healing process.
Efficiency and Versatility: BFR training is highly adaptable and can be more time-efficient than traditional strength training methods. It provides a viable option for individuals with limited access to heavy weights or busy schedules to maintain or improve physical fitness.
Potential Risks
While BFR training offers numerous benefits, it's important to be aware of potential risks and manage them effectively. BFR training is generally safe when blood flow is restricted for a few minutes rather than extended periods, and its safety profile is comparable to traditional high-load exercise.
Risk of Venous Thromboembolism: Restricting venous blood flow during BFR training has the potential to increase the risk of blood clots. However, current evidence does not suggest a significant increase in this risk.
Muscle Damage: Incorrect use of BFR training can lead to extensive muscle damage and the possibility of rhabdomyolysis, a serious syndrome resulting from muscle injury. However, muscle biopsies after BFR training have shown intact muscle fibres, indicating no structural damage.
Neuropraxia: Temporary nerve impairment may occur due to pressure from the bands used in BFR training.
Cuff Pressures for Blood Flow Restriction Training
Applying the correct cuff pressure in BFR training is vital for ensuring both effectiveness and safety. Different pressures are typically required for upper and lower body exercises due to the varying sizes and blood flow requirements of the muscles involved. It is crucial to avoid excessively high pressures that completely occlude blood flow or cause discomfort.
Determining the Correct Pressures
The appropriate pressure for BFR training varies from person to person and depends on factors like cuff width, limb circumference, and blood pressure. It is often recommended to determine pressure based on a percentage of an individual's limb occlusion pressure (LOP), which is the minimum pressure required to halt blood flow to the limb. Doppler ultrasound devices can be used to measure LOP by gradually increasing cuff pressure until the pulse in the distal part of the limb is no longer detectable. A pressure range of 40% to 80% of an individual's LOP is commonly used during BFR training, with higher pressure for lower body exercises and lower pressure for upper body exercises. In the absence of Doppler ultrasound, a subjective scale can be used, aiming for a perceived tightness of around 7 out of 10.
It is important to seek professional guidance when determining the correct pressures for BFR training to mitigate potential risks. Recommended band providers often offer automatic pumps that can determine and adjust cuff pressures automatically.
Training Regime
The implementation of a BFR training regimen should consider an individual's physical condition, goals, and recovery ability. A typical BFR session lasts up to 20 minutes after the cuff has been inflated. Longer durations, up to 40 minutes, can be utilised for aerobic exercises with lower cuff pressures, but it is advisable to seek professional advice before attempting this.
A typical BFR routine might involve low-load resistance training with an intensity of 20-30% of one repetition maximum. This exercise can be performed for 15-30 repetitions across 3-5 sets, with 30-second rest intervals between sets. A controlled movement tempo of 1-1.5 seconds up and 1-1.5 seconds down is recommended. Slower pacing with lighter weights can still effectively stimulate muscle growth as it maintains sufficient time under tension to activate growth signalling pathways.
In the context of rehabilitation, BFR training may begin passively, gradually incorporating slow walking exercises, and eventually progressing to resistance exercises as strength and tolerance improve. High-load exercises can be included as the individual recovers further.
Conclusion
BFR training presents an exciting avenue for strength gain and muscle hypertrophy, particularly for individuals who are unable to engage in high-load exercises. Adhering to guidelines and seeking professional guidance can ensure both the safety and effectiveness of this training method. With its potential to optimise fitness outcomes and aid in rehabilitation, BFR training holds promise as a valuable addition to diverse exercise routines.
Further Reading
Sato Y. The history and future of KAATSU training. Int J KAATSU Train Res. 2005;1(1):1-5. DOI
Lixandrao ME, Ugrinowitsch C, Berton R, et al. Magnitude of muscle strength and mass adaptations between high-load resistance training versus low-load resistance training associated with blood-flow restriction: a systematic review and meta-analysis. Sports Med. 2018;48(2):361-378. PubMed
Loenneke JP, Fahs CA, Rossow LM, Abe T, Bemben MG. The anabolic benefits of venous blood flow restriction training may be induced by muscle cell swelling. Med Hypotheses. 2012;78(1):151-154. PubMed
Jessee MB, Buckner SL, Mouser JG, et al. Muscle adaptations to high-load training and very low-load training with and without blood flow restriction. Front Physiol. 2018;9:1448. PubMed
Tobias IS, Galpin AJ. Moving human muscle physiology research forward: an evaluation of fiber type-specific protein research methodologies. Am J Physiol Cell Physiol. 2020;319(5):C858-C876. PubMed
Park S, Kim JK, Choi HM, Kim HG, Beekley MD, Nho H. Increase in maximal oxygen uptake following 2-week walk training with blood flow occlusion in athletes. Eur J Appl Physiol. 2010;109(4):591-600. PubMed
Hughes L, Paton B, Rosenblatt B, Gissane C, Patterson SD. Blood flow restriction training in clinical musculoskeletal rehabilitation: a systematic review and meta-analysis. Br J Sports Med. 2017;51(13):1003-1011. PubMed
Nakajima T, Kurano M, Iida H, et al. Use and safety of KAATSU training: Results of a national survey. Int J KAATSU Train Res. 2006;2(1):5-13. DOI
Loenneke JP, Pujol TJ. The Use of Occlusion Training to Produce Muscle Hypertrophy. Strength Cond J. 2009;31(3):77-84. DOI
Horiuchi M, Stoner L, Poles J. The effect of four weeks blood flow restricted resistance training on macro- and micro-vascular function in healthy, young men. Eur J Appl Physiol. 2023. PubMed
Patterson SD, Hughes L, Warmington S, et al. Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety. Front Physiol. 2019;10:533. PubMed
Loenneke JP, Wilson JM, Marin PJ, Zourdos MC, Bemben MG. Low intensity blood flow restriction training: a meta-analysis. Eur J Appl Physiol. 2012;112(5):1849-1859. PubMed
Abe T, Kearns CF, Sato Y. Muscle size and strength are increased following walk training with restricted venous blood flow from the leg muscle, Kaatsu-walk training. J Appl Physiol. 2006;100(5):1460-1466. PubMed
de Queiros VS, Rolnick N, Sabag A, et al. Acute Responses in Blood Flow Restriction Low-intensity Aerobic Training: A Meta-analysis. Int J Sports Med. 2023. PubMed
Spitz RW, Bell ZW, Wong V, et al. Strength testing or strength training: considerations for future research. Physiol Meas. 2020;41(9). PubMed
Loenneke JP, Kim D, Fahs CA, et al. Effects of exercise with and without different degrees of blood flow restriction on torque and muscle activation. Muscle Nerve. 2015;51(5):713-721. PubMed
Sun D, Yang T. Semi-Squat Exercises with Varying Levels of Arterial Occlusion Pressure during Blood Flow Restriction Training Induce a Post-Activation Performance Enhancement and Improve Vertical Height Jump in Female Football Players. J Sports Sci Med. 2023;22(2):212-225. PubMed
Spitz RW, Wong V, Bell ZW, et al. Blood Flow Restricted Exercise and Discomfort: A Review. J Strength Cond Res. 2022;36(3):871-879. PubMed

By
Dr Ran Crooke
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